P21-activated kinase 3 (PAK3) gene mutations are linked to several neurodevelopmental disorders, but the underlying mechanisms remain unclear.In this study, we used a tetracycline-inducible system to control the expression of a mutant PAK3 (mPAK3) protein in immediate early gene, namely cFos, positive cells to disrupt PAK signaling, specifically in

Abstract Introduction Spheno-orbital meningiomas are characterized by bone invasion with extensive hyperostosis and possible encroachment into the orbit, infra-temporal fossa, and/or the cavernous sinus that render total surgical excision challenging.The surgical technique utilized is a key factor facilitating complete resection and hence improveme

Providing real-time and accurate travel time information of transit vehicles can be very helpful as it assists passengers in planning their trips to minimize waiting times.The purpose of this research is to develop and compare dynamic travel time prediction models which can provide accurate prediction of bus travel time in order to give real-time i

Many Atlantic salmon Salmo salar populations in Europe are threatened by previous stocking with foreign hatchery strains.Temporal patterns of genetic characteristics of salmon from northern Spain, the southernmost European populations, Luminous Affection Couple Ring were compared before and after species decline and heavy stocking with specimens fr

This article is dedicated to analyzing the effectiveness of the reforms in the teacher salary payment system in Kazakhstan and its impact on the quality of pedagogical activity, as well as the possibility of attracting educators from universities and professionals from other sectors to schools by increasing salaries.The results are based on regiona